Creoptix WAVE / Creoptix WAVEdelta

Label-free data like you’ve never seen before. 

 


    Creoptix WAVE   Creoptix WAVE
         
    Creoptix WAVE   Creoptix WAVEdelta
Flow Channels   2, serial   4, parallel
Noise   < 0.015 pg/mm2 @ 10Hz   < 0.01 pg/mm2 @ 1Hz
Analysis Temp. Range   15–40°C   4–45°C
Running Buffers   1   4
Built-In Degasser   No   Yes
Crude Sample Robustness   Yes   Yes
Fast Off-Rates   5/s   5/s
Maximum Flow Rate   200 µl/min   400 µl/min

 

 

Creoptix WAVE / Creoptix WAVEdelta

Label-free data like you’ve never seen before. 

 


    Creoptix WAVE Creoptix WAVE
       
    Creoptix
WAVE
Creoptix
WAVEdelta
Flow
Channel
  2, serial 4, parallel
Noise   < 0.015 pg
/mm2
@ 10Hz
< 0.01 pg
/mm2
@ 1Hz
Analysis
Temp. Range
  15–40°C 4–45°C
Running
Buffers
  1 4
Built-In
Degasser
  No Yes
Crude Sample
Robustness
  Yes Yes
Fast
Off-Rates
  5/s 5/s
Maximum
Flow Rate
  200 µl/min 400 µl/min

 

By seamlessly integrating a temperature-controlled autosampler and a powerful measuring device, WAVE offers the sensitivity and flexibility to adapt perfectly to virtually any application.

The system puts a breakthrough level of kinetics analysis at your fingertips by pushing the boundaries of affinity range and sample compatibility. Data quality is higher than ever before leading to more meaningful screening hits, optimizing interaction analysis and creating new inroads for scientific research.

WAVE’s unique capabilities meet the demanding needs of the drug discovery industry especially in:

  • Kinetic analysis of membrane proteins, like GPCR, in crude membranes
  • Fragment-based screening
  • Weak binding small molecule drugs
  • Large drug targets
  • Kinetic analysis of virus or virus-like-particles
  • Kinetics in crude matrices, like serum
  • Binding analysis at low concentrations and slow dissociation kinetics

 

Weak binders, strong data.

Ligand: Carbonic Anhydrase II (29 kDa)
Analyte: Methylsulfonamide (95.1 Da), koff = 2.79 sec-1

With the industry’s highest sensitivity, WAVE offers a whole new level of previously unattainable interaction data.

  • Instruments

    Creoptix WAVE
    Label-free data like you’ve never seen before.

  • Sensors

    Creoptix WAVEchips
    Innovative combination of microfluidics and sensor in a single disposable cartridge.

  • Software

    Creoptix WAVEcontrol
    Intuitive, workflow-based design offering both flexibility and functionality.