Creoptix proudly announces three new Tech Notes demonstrating the benefits of the Creoptix™ WAVE system for molecular interaction analysis:
Fast Off-Rates: Based on very fast injection processes, the Creoptix™ WAVE enables reliable analysis of off-rates of 5 per second! This now allows for off-rate screening and ranking of weak binders such as fragments in a very early discovery process.
Kinetics at High Serum: The innovative disposable microfluidics of the Creoptix™ WAVE provides very high robustness against complex matrices and does not clog at even 100% untreated blood serum. This allows kinetic analysis at much higher serum concentrations than ever before.
Avoiding Mass Transport: Kinetic data quality is significantly impaired by mass transport due to the high immobilization levels required. Thanks to the exceptionally high sensitivity of the Creoptix™ WAVE, reliable kinetics below 1 pg/mm2 are possible and immobilization levels can be markedly reduced. This not only reduces sample consumption but also mass transport limitation.